Neuro Science    

 

 

 

Brain Structure/Brain Anatomy

Brain Structure in this note refer specifically to the structure of Human brain. It is not general term applies to all animals. There are some animals that does not have brain (even though they have their own nervous system). There are a lot of animal species that has brain but the detailed structure of them are different among species.

In this note, I would like to focus on Human brain structure since my main intereste lies in human neurosience more specifically in understanding myself.

However it is not the purpose (and out of my capability) to describe the full details of human brain like the Brain Anatomy text book in medical school. It is not possible for me to dig into that far since I have never been trained in medical school, but plan to provide information bare enough to understand technical articles / watch lectures on YouTube.. and (hopefully) be enough for those exposed to basic anatomy in biology course.

Why I don't like Anatomy ? and How to get it over ?

There might be some people who likes Anatomy and memorize all the name of all those names to the very tiny parts at the corner without much difficulties and stress. But unfortunately I am not that type of person and a lot of readers would be similar type as I am.

I started thinking of why I don't like it and came out with a few reasons :

  • I am not so interested in it
  • The vacabularies in Anatomy does not look familiar. I am not a native engilish speaker and am struggling with english, but most of the vocabularies in anatomy is even worse than english to me since they are mostly based on Latin and Greek.

Unfortunately I don't have any one shot solution for any of these. Especially for the first item, I didn't even try to find the solution because I know there is no clear solution for it. But I think there would at least something to try for the second one. It is to make my own word book for Latin and Greek try to remorize it whenever I see those words from the labels on the pictures in Anatomy books. I would not recommend you to write down hundreds of Latin/Greek words and try to remember it by rote memory. Just put those words in your notebook whenever you see the new words and try to check on the meaning of the words in Latin/Greek dictionary. Some references under Dictionary section may help you with this.

One good thing for this and building a Greek/Latin vacabulary in your memory would help you not only anantomy but also for other subjects (like biology, organic chemistry, biochemistry etc).

Why we should study / learn on Brain Anatomy ?

If you are not a big fan of Anatomy, you would have ask this to yourself many times and try to avoid looking into brain anatomy even though you are strongly interested in neuroscience / brain science.  Personally I am not a big fan of anatomy and extremely poor at anything that requires a certain degree of rote memory. so I asked the same questions over and over to myself.  Unfortunately I haven't found any way / reason to avoid studying brain anatomy to study about neuroscience / brain science. A few reasons why I should study on the anatomy are listed below :

  • Most of research papers, text book, articles are refering to some specific regions in brain (or in our nervous system) when they are explain about memory procedure, neuro placiticity etc. But most of them just mentions about the name of the region without showing any image/drawings etc.
  • If you just read these text without imagining the region in your mind, it would be hard to follow through the stories in the text. Even though you managed to follow through the stories when you are reading it, the memory would go away very soon if you don't associate the story (verval description) with the image of the region in the brain.

In short, regardless of whether you like or not, a certain level knowledge of brain anatomy is a mandate and you cannot avoid it.

How to study/learn on Brain  Anatomy ?

If you are a student in medical program, there wouldn't be much thing I can advise or propose mainly because there wouldn't be much options except just following whatever you are asked to do in your program. To be honest, I don't think the way you are asked to do in most of school program is the best and the most efficient way to learn anything, but it may be good enough to memorize many things in relatively short period. (I don't know how long you can maintain/retain the memory after the end of the course).

I don't think the way we are being tought or trained at school is the best/efficient way in terms of neurocience / educational psychology. Interestingly even the educational program about neuroscience does not seem to go in such a way that is suggested to be efficient in the theory/research of neuroscience/educational psychology.

My personal way of learning / memorizing about brain anatomy is as follows. I don't know if this is the best way, but it seems the best fit for myself and I don't feel any stress about this. I have extremly poor memory and I extremly hate the process of rote memorization.  But doing this way, I see myself getting rapidly familiar with the overal brain anatomy without getting any stress. Of course, I am not at the expert level in this area, but I think I reached pretty good position as an hobbiest.

  • Read or watch anything about Brain Science that you are interested.
  • If any of them talk about any brain region with whtich you are not familiar without any picture, check out this note or any other reference showing the image of the region. Don't try to memorize it, just confirm the region in the image. ==> One of the best way is ... take out pen and paper and draw the structure on the paper and label each of the region in your own writing. You don't have to do it every time... just once or twice of drawing in your own hand would be great help. In my case, I purchased a sketch pad and draw pictures on power point slide and use the drawings in my note here.
  • If you do this practice several time, you would getting familiar with the region and terminology(name) of the region even though you don't memorize it.
  • If you continue to the practice even further, you would notice that you start memorizing even though you didn't try ==> this is when the image about the region converted into long term memory and stored in your brain.
  • If you do this further, you would get overall framework about the overal structure of the region inside your brain. this kind of mental framework is called schema. That is, you start building your own scheme about the brain region you are intersted.
  • Once you are building up this kind of schema, it will become more easier to learn/memorize about the new regions fuctionally or locationally related to the brain region that are already in your long term memory.

NOTE :  I agree that this way of studying would take much longer time comparing to what you are asked to do in your school program, but I am pretty sure that it would be much less stressful and help you to keep your interest and maintain/retain the memory much longer.

Do you know how the brain placed inside the skull ?

I think everybody would have seen a picture of a human brain as shown below. Do you know which is front (the part right inside your forehead) and which is back (the part right inside your backhead) ? Don't be disappointed if you don't know. I myself had been confused for a long, long time. Sometimes I put the labels on the picture indicating 'front' and 'back', but soon get confused again if I see the picture with no label.

Finally I found my own trick to remember the front and back of the brain image. It is to get the picture (or drawing it in your own would be even better) with skull as shown below. You don't even label the front and back. Just imprint this image in your brain (memory) as a picture and recall this image whenever you get confused.

Vocabularies for Directions

I think the first thing that we should be familiar with would be a list of words indicating the directions since those words would pop up in almost every basic materials (articles, lectures etc). Again.. most of the words for the direction are also Greek/Latin based. A short list of those words representing the directions are listed below.

  • ROSTRAL / ANTERIOR : towards the 'head' end
  • CAUDAL / POSTERIOR : towards the 'tail' end
  • DORSAL / SUPERIOR : back or upper surface
  • VENTRAL / INFERIOR : belly or under surface
  • MEDIAL : towards the middle line
  • LATERAL : towards the side

Applying these words to the highest level brain structre is as follows : Just try to remember the whole image with label in your brain until you can recall these images automatically whenever you see those words.

 

 

 

Structure of Cerebral Cortex

Probably one of the most important picture that you should be familiar with would be this. The cerebral cortex(surface) of our brain can be divided into several import area as shown below. Whatever texts or video you would read/watch about neuroscience, you would see at least one of the names (labels) shown here.

NOTE : If you have chance to read research articles or papers, there would be cases where you don't see any of these names. But it is because those articles or papers refers to a very specific area within one of these area with very specialized name.

Planar / Sectional View of the Brain

Untill we have hologram as our everyday display, we would need to rely on represending everything (the brain as well) in 2 dimensional display. Even it the computer display and text book drawing some 3D objects it is still the prjection of the 3D object onto 2D plane, not real 3D. One common way is to help you to get an idea of a 3D object in 2D display is to cut through the 3D object with various 2D plane and let your brain to imagine it in 3D in your brain.

Unlike other parts of nervous system (e.g, spinal cord, peripheral nerves etc), brain is a bulky 3D object with very complicated internal structure. We would need to cut through it in various different angles to get the full picture. So it has been a long practice to get the image of a cut-through image by anatomoy or by brain imaging (e.g, MRI, CT, fMRI) and you would need quite a lot of practice to interpret those cut-through images in the context of 3D brain.

A few of the most frequently used cut-through plane are shown as below. You may have seen such a description like "this is sagittal section of the brain" or "this is coronal section of the brain" etc.

Image Source : LEC 1A - Anatomy Of The Nervous System

Following is an example of the sectional image with Coronal, Sggital, Horizontal plane. You may need to quite a lot of practice to identify a certan part of brain region (e.g, hypothalmus or hippocampus etc) in each sectional image. For example, some of the region would be seen only in a specific section, not in other sections.

Image Source : LEC 1A - Anatomy Of The Nervous System

Brodmann's Map

I think you may have seen most of the drawings / pictures in previous sections when you are reading / studying neuroscience as an hobbiest. However there wouldn't be many cases where you see a little bit more detailed classification of brain reason as shown below. This is called Brodmann's map naming after the scientist who created this map. If you can figure out a reason just by looking at the numbers in other text and lecture or at least know what the number mean and find out any document showing the details, you would consider yourself as pretty experienced in neuroscience.  I am not expecting you to memorize all the details of this map. It would be enough if you know what to look for when you see the comments like 'Broadmann map 17' or just the number 17.

Image Source : Hallucinations Experienced by Visually Impaired: Charles Bonnet Syndrome (ResearchGate)

This is the table with the name/label for each of the numbered area shown in the map showing a little bit of description.

Brodmann area

Abbreviation

Name of the Brodmann Area

BA01

S1

Primary somatosensory cortex

BA02

S2

Secondary Somatosensory cortex

BA03

S3

Tertiary Somatosensory cortex

BA04

M1

Primary motor cortex

BA05

SPS

Superior parietal sulcus

BA06

SMA

Supplimentary motor area

BA07

SPG

Superior Parietal Gyrus

BA08

Pre-SMA

Pre-supplimentary motor area

BA09

DLPFC

Dorsolateral prefrontal cortex

BA10

FPC

Fronto-parietal cortex

BA11

OFC

Orbital frontal cortex

BA13

Insula

Insula

BA17

V1

Primary visual cortex

BA18

V2

Secondary visual cortex

BA19

Cuneus

Cuneus

BA20

ITG

Inferior temporal gyrus

BA21

MTG

Medial temporal gyrus

BA22

STG

Superior temporal gyrus

BA23

PCC1

Posterior cingulate cortex1

BA24

dACC

Dorsal anterior cingulate cortex

BA25

sgACC

Subgenual anterior cingulate cortex

BA27

PHC1

Parahippocampal gyrus

BA28

HIP1

Hippocampal area

BA29

RSC1

Retrosplenial cortex1

BA30

RSC2

Retrosplenial cortex2

BA31

PCC2

Posterior cingulate cortex2

BA32

prACC

Pregenual anterior cingulate cortex

BA33

rACC

Rostral anterior cingulate cortex

BA34

HIP

Hippocampus

BA35

HIP2

Hippocampus area2

BA36

PHC2

Parahippocampal gyrus2

BA37

OTC

Occipital-temporal cortex

BA38

TP

Temporal pole

BA39

AG

Angular gyrus

BA40

IPS

Intra-parietal sulcus

BA41

A1

Primary auditory cortex

BA42

A2

Secondary auditory cortex

BA43

PCG

Postcentral gyrus

BA44

OPCG

Opercular part of inferior frontal gyrus

BA45

IFG

Inferior frontal gyrus

BA46

MPFC

Medial prefrontal cortex

BA47

VLPFC

Ventro-lateral prefrontal cortex

Reference

Neuro Anatomy Web Tools

 

 

 

YouTube

 

 

 

Dictionary